HN Jobs

Prolific Machines | Senior Software Platform Engineer | On-site mostly (Emeryville, CA) | Full-time | $160k–$210k + equity We use light to control how living cells produce therapeutic proteins — optogenetic cell engineering, custom illumination hardware, and real-time ML bioprocess control — to drive down cost and scale up production of next-generation therapies. With our technology scaling from the lab to the real world of biomanufacturing, we're now hiring a foundational software engineer to build the platform tying together our hardware, firmware, cloud, and internal tooling — high ownership over architecture and direction. This is a systems role across the hardware/software boundary (not web/SaaS), working directly with embedded, mechanical, data, and even bioprocess engineers. Looking for: strong systems thinking; Python + one of TS/Go/Rust; cloud-connected services; comfort interfacing and debugging software against hardware (serial, TCP/IP); Linux. MS + 5 yrs or BS + 7 yrs. Bonus: Industrial IoT (MQTT Sparkplug B, OPC UA, SCADA/MES), regulated-industry data integrity (21 CFR Part 11, GAMP 5), or embedded C/C++. Apply: https://jobs.lever.co/prolific-machines/6d71f9d0-7248-4449-8... Happy to answer questions: matt dot fay at prolific dash machines dot com.